The Immunization Initiative at MCN promotes improving childhood, adolescent, and adult immunization coverage levels among migrant and other mobile underserved populations. During the course of the initiative, anecdotal and documented evidence of an increase in the Hispanic indigenous population in United States and outside California surfaced from various sources. A separate initiative emerged, to design and develop a piece of educational material specifically for this population. This article, published in Streamline (March-April, 2009) discusses this initiative.